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Correct answer: True

Data show that adherence to the Cologuard test is 71% for the first screening, and it grows to 86% and 91% for the second and third screening, respectively, as established by real-world data.1,2*

Sorry, that’s incorrect.

Correct answer: True

For the first screening with the Cologuard test, data show that adherence is 71%.1 As reported in real-world data, the adherence rate for the second screening 3 years later rises to 86%; and continues to increase to 91% for the third screening.2*

References and footnotes

  • *Based on a retrospective cohort study of 326,329 patients aged 45-75 at average risk for CRC who received a Cologuard kit between January 2017 and September 2023 and who had a previous Cologuard test with a negative result.2
  • 1.Le QA, Greene M, Gohil S, et al. Adherence to multi-target stool DNA testing for colorectal cancer screening in the United States. Int J Colorectal Dis. 2025;40(1):16.
  • 2.Greene M, Gohil S, López JVR, et al. High adherence to repeat multitarget stool DNA testing and follow-up colonoscopy in average-risk United States adults: results from a nationally insured cohort. Clin Ther. Published online November 28, 2025.